Posts Tagged ‘Adnan Hyder’


Research Ethics Committees in Nigeria: A Survey of Operations, Functions, and Needs

Thursday, August 31st, 2017

Abstract: Heightened global commitment to research on diseases such as HIV/AIDS, tuberculosis, and malaria has led to increased research over the past decade in many African countries, including Nigeria. This increase in research has led to debates about the ethics of health research in resource-poor or developing countries and has drawn further attention to existing ethical review processes. This study was undertaken to describe and benchmark the operational and organizational structures as well as functions of research ethics committees (RECs) in Nigeria. The article explores the factors that contribute to REC conformity with the Nigerian National Ethics Code and World Health Organization (WHO) guidelines for RECs. Data were collected using a self-administered, semistructured questionnaire. A descriptive analysis was conducted, and Fisher’s exact tests performed to assess associations between selected REC characteristics and the degree of conformity to applicable national and international requirements. Eighty percent of RECs (20 out of 25) had standard operating procedures, while 68% (17 out of 25) met at least quarterly and provided final review determinations within three months. RECs with committee chairs who had prior bioethics training were more likely to have operations conforming to the WHO and the Nigerian ethics guidelines. Overall, this study suggests that there is variability in the degree to which operations and functions of RECs in Nigeria conform to the Nigerian National Code and WHO guidelines.

 

Research Ethics Committees in Nigeria: A Survey of Operations, Functions, and Needs,. Aminu A. Yakubu, Adnan A. Hyder, Joseph Ali, and Nancy Kass. IRB: Ethics & Human Research. 2017. May-June 2017 Volume: 39, Issue: 3

A case study of researchers’ knowledge and opinions about the ethical review process for research in Botswana

Monday, November 7th, 2016

Abstract Most countries, including Botswana, have established Institutional Review Boards (IRBs) to provide oversight of research involving human beings. Although much has been published on the structure and function of IRBs around the world, there is less literature that empirically describes the perspectives of stakeholders in low- and middle-income country (LMIC) settings regarding IRB processes. In this study, we employed primarily quantitative methods to examine the perceptions of researchers at the University of Botswana (UB) about the review of research protocols by local IRBs. Data were collected using a web-based survey (SurveyMonkey). This was a preliminary effort to document some of the emerging experiences of researchers with ethics review in a context where both research and research oversight are relatively new. Findings from 85 researchers indicate that researchers recognized the need for an IRB to review all human research protocols, expressed the need for research ethics training, experienced high rates of approval at government ministries and UB, and generally believed that ethics review processes can help researchers themselves better understand and appreciate research ethics in general. Though only about one-quarter of respondents reported a more positive view of research ethics after interacting with the UB IRB, 56.5 percent reported no change. In contexts where IRBs have recently been established, it can be particularly important to document the perspectives of researchers in order to align expectations with capabilities, and identify areas where IRBs can improve operations. Future efforts to advance research ethics and ethical review in Botswana should include establishing research ethics training requirements and courses for researchers, increasing investment in IRBs and their training, further developing institutional and national research ethics policies, and formalizing agreements between IRBs and others involved in research oversight in the country to support coordinated review.

Webinar: The Ethics of Health Systems Research

Wednesday, September 17th, 2014

On August 5th, 2014, Dr. Adnan Hyder conducted a Johns Hopkins-Fogarty African Bioethics Training Program (FABTP) webinar, in conjunction with Health Systems Global, the Berman Institute of Bioethics, the Bloomberg School of Public Health, and Future Health Systems,  in which he discussed ethical complexities of health systems research.  Nearly 70 participants from around the world joined for a lively presentation and discussion.


Dr. Hyder examined nine aspects of HSR and the ethics questions that may accompany each of these elements.  The webinar provided an overview of HSR methods, measures, and research subjects (human and non-human). Dr. Hyder also explored units of interventions, data collection and informed consent, discussing the complexities of obtaining consent at the community level. Further, he discussed the absence of “pure” control groups in HSR and alternative means of comparing groups that do and do not receive interventions. He introduced risk assessment, vulnerabilities of certain groups, and evaluation types.


To watch a recording of the webinar and read more, click here.

Research Ethics Capacity Development in Africa: Exploring a Model for Individual Success

Tuesday, July 17th, 2012

Why Mothers Choose to Enroll Their Children in Malaria Clinical Studies and the Involvement of Relatives in Decision Making: Evidence from Malawi

Wednesday, September 8th, 2010

The structure and function of research ethics committees in Africa: A case study

Wednesday, September 8th, 2010

The female condom society and public health; A commentary from Sub-Saharan Africa

Monday, August 30th, 2010